Have you tried running those games in windowed mode to see if they work better?
The reason I am asking is that sometime between the 20.8.x drivers and 20.11.x drivers my MSI 5700XT ended up stuck with the GPU clock around 6-20 MHz in many (but not all) games instead of its normal 1700+ MHz GPU clock. This caused the games to run at about 1 fps according to things like the Steam overlay, and everything would feel like it was half frozen. The 21.2.3 drivers did not fix this, and neither did a complete reinstall of Windows.
I only realized what the problem was when I started running GPU-Z on my second monitor while launching the games, so you could try having GPU-Z open with the Sensor tab active and see if the GPU clock changes at all or seems stuck on a low value.
It didn't happen in every game for me (Yakuza 0 ran perfectly normal the whole time, for some reason) but almost all games had that issue in fullscreen mode. Windowed mode or borderless windowed mode worked fine in many games, but some games (Skyrim or Fallout 4, for example) would not work properly even in windowed/borderless mode.
I removed the GPU driver with DDU and went back to 20.8.1 from July and now the GPU clock is around 700 MHz in idle and goes up properly during games, so they run fine again. I am running Windows 7 on this particular PC, but I figure it's worth a try even on Windows 10.
Edit: Alt+Enter might help switch between fullscreen and windowed on games where there's no launcher to help with this, but it can be tricky to get it recognized if it's stuck at <1 fps.
