Your system will run faster with the Ryzen 5 5600. More cores & threads = Faster!
The way I understand it, you need a MoBo that supports PCIe4 to use it with the 5 5600. You can still use the 5 5600 but you will still only get PCIe3 bus speed. Definately check your Mobo Specs, I think some 400 series boards do use PCIe4. I'm using a Asrock x370 Taichi with a new 5 5500. I would have done the 5 5600g but have no video out on my MoBo. Then there is the price...