Update:
After observing the issue a bit closer, it always happens, when Windows Taskmanager shows 15,8 GB out of 32 GB used.
It then starts acting weird by not loading thumbnails on VOD sites like twitch or youtube streams.
To rule out hardware issues with the ram, I've run Memtest86+ over night, which passed 7 times:
After that, I did again check systemfile integrity:
and DISM:
The problem persists, even after installing Windows on a different physical drive which was the only drive attached, other than my Samsung 980 Pro NVMe.
The problem itself feels like the memory issue which Geforce GTX 970 had, when a game tried to allocate more than 3,5 GB vram: as soon as the threshold is reached or exceeded, performance drops significantly.
With my system memory behaviour, I can effectively only use 16 GB ram and I have to reboot if it uses more, because the entire system starts slowing down and feel "laggy" the more ram is used.
Observing list:
-disabled virtualization in bios
-set the base clock speed to a fixed 100 MHz instead of AUTO
-set the FCLK to 1600 MHz instead of AUTO
-adjusted subtimings (tRC, tFAW on memory timings that weren't accepted after loading xmp profile)
If that doesnt help, To-do list:
- test both memory sticks in channel A and B respectively as single channel config
- update BIOS to a newer version (current is AGESA 1.2.0.A which includes X3D support) which I consider a "hail mary" option.