Got the notification today to update to 20.2.2. The Radeon software downloaded them, and soon after clicking 'install' my system crashed and rebooted.
After logon, I tried again and the installer said it failed. It did something though, because my Firefox theme got disabled and I got an error popup from Steam.
Steam.exe - Bad Image
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C:\Windows\System32\detoured.dll is either not designed to run on Windows or it contains an error. Try installing the program again using the original installation media or contact your system administrator or the software vendor for support. Error status 0xc000012f.
I did a DISM and SFC to make sure Windows was OK, and both passed.
I then downloaded the Radeon driver installer from the website. The install succeeded, but I still got the Steam error, and also another error popup at login.
AMD:CCC-AEMCapturingWindow: RadeonSoftware.exe - Bad Image
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C:\Windows\SYSTEM32\mantle64.dll is either not designed to run on Windows or it contains an error. Try installing the program again using the original installation media or contact your system administrator or the software vendor for support. Error status 0xc000012f.
I used system restore to go back to before the initial driver update and now I'm back on driver version 20.1.3 and everything is back to normal.