Not sure about having more than one monitor but try using the 22.10.3 driver and do the following:
1. Disable Hardware Acceleration on everything (Web browser, Discord, Zoom, etc.)
2. Disable Radeon Image Sharpening in the AMD Software
3. Disable Radeon Enhanced Sync in the AMD Software
I used to get blackscreens with my RX 6750 XT but since doing all of the above I haven't had it for months now. For some people newer drivers like 22.11.1 or 22.11.2 cause no blackscreens but for me I'm getting it even after doing the above mentioned steps.