There has been talk about AMD helping retailers mitigate bots and the like, but otherwise I don't think the method of ordering will be any different.
Ironically, using bots is the best way to get stock alerts, so you can jump in and buy one as soon as it's available. That's how I managed to get a 6900 XT.
On release day, however, you'll just want to manually check at around 9am EDT. Notification bots are useful afterwards when you don't know when stock will come back in.
