Using adrenalin 18.12.3 I have found about once per day my gpu/memory clocks get stuck in low power states and require a full system reset. Whether i use the Balanced Profile, Custom with automatic undervolt or a full custom with my own speed bins defined.
Each profile exhibits the same behavior. The memory gets stuck @ 167mhz and the gpu clock 1100mhz i believe. But most of the time the gpu clock is ok it's just the memory that becomes stuck.
Launching a game, any game will have very low performance around 10-30fps when i'm normally running 70fps locked.
I use an LG ultrawide monitor 2560x1080 with freesync and running @ 75hz.
my gpu is an asus rog strix vega56.
asus rog crosshair hero vii
16gb gskill 3466mhz
windows 10 v1809
As a side note, this driver also prevents my monitor from entering sleep. The lock screen will come up after 10 minutes so the pc is inactive but the monitor just stays on indefinately.