I was having issues with my Visual Studio and Notepad++ because a commonly used shortcut stopped working. Ctrl+Shift+L is a delete line shortcut. ReLive doesn't use this exact shortcut but it seems to capture and block the shortcut from passing to other apps - even when ReLive is disabled/turned off (but still installed).
If you disable the 2 ReLive background processes: AMD ReLive: Desktop Overlay and AMD ReLive: Host Application - in that order otherwise they restart
As soon as that is done, Ctrl+Shift+L will work again.
Please fix, otherwise ReLive will have to be uninstalled.