I upgraded from a HD7850 to a R9 380X, and this is the result
I swapped the PSU to rule out power supply issues.
I tried to remove anything AMD, and reinstall everything from scratch.. I tried to run with the Catalyst drivers that came with the card.
I tried with older Crimson drivers, I tried with the 16.9.2 and 16.9.10 hotfix drivers.
Still no resolve.
There has been no way of contacting AMD, all I get are these forums, and it has frustrated me to the brink of madness.
So what now, well I am going to send it back to where I bought it, and most likely will get it swapped for a new card, if they also get an error.
If they don't get an error, I still got my 14 day return policy rights, and would have to get the money returned and buy Nvidia for the first time in 10 years.
Your primary support will come from the card's manufacturer (XFX, Sapphire, MSI, etc), as AMD only makes the GPUs which are sold in trays to the board partners.