I upgraded from a HD7850 to a R9 380X, and this is the result
I swapped the PSU to rule out power supply issues.
I tried to remove anything AMD, and reinstall everything from scratch.. I tried to run with the Catalyst drivers that came with the card.
I tried with older Crimson drivers, I tried with the 16.9.2 and 16.9.10 hotfix drivers.
Still no resolve.
There has been no way of contacting AMD, all I get are these forums, and it has frustrated me to the brink of madness.
So what now, well I am going to send it back to where I bought it, and most likely will get it swapped for a new card, if they also get an error.
If they don't get an error, I still got my 14 day return policy rights, and would have to get the money returned and buy Nvidia for the first time in 10 years.