Have you tried uninstalling all previous drivers before installing any new ones? I usually find this helps.
Before uninstalling any old drivers, make sure you have your new ones downloaded from AMD.com (both GPU and chipset drivers), and that the 16.7.3 are compatible with your system. If this is good, then this is what I would do:
Go to "Programs and Features" menu, and uninstall all AMD related software drivers, usually by clicking on the AMD Install Manager, and then clicking "uninstall" button towards the top of that menu. After that, restart. Then run the AMD Clean Uninstall Utility from here: AMD Clean Uninstall Utility (I usually download this utility first before doing any uninstalls). This should uninstall all AMD driver software from your computer, and leave you with a fresh place to start.
Then install your GPU drivers first, and then your chipset drivers. If you run into any issues, you can either try these steps again, or install older drivers, and sit on those until a newer driver comes out that is a bit more stable. I had some issues installing my 16.7.3 drivers this time around, and it took me a few tries of repeating these steps to get them to install without any issues. So, it may take a few times if you are determined to have the new ones. If not, roll back and sit on some older ones for a while until something newer comes out.
I wish you the best of luck, and I hope I was helpful.
Microsoft Windows 10 Pro RS1_RELEASE 14393 clean installation.
Radeon Software (Crimson Edition 16.7.3) 7/28/2016 - successfully installed
AMD Chipset Drivers (Crimson Edition 16.7.3) 7/28/2016 - installation failed
I would try a previous driver version at this point.
Okay, When I attempt to install the new 16.7.3 version, I am being told it cannot open the install manager because another instance of it is already open. I have restarted and shut off, checked start-up area and processes... nope not open... and it gave me the same error.
Running x2 r9 290.
x2 r9 290
msi z97 gaming 9ac motherboard
Have you tried uninstalling all drivers before installing anything new? I know this seems obvious, but it seems to me this error would be impossible if all AMD software was uninstalled off the computer before installing any new drivers.
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It might be because you are using the Windows Insider build. Have you enabled secure boot?
Secure boot disable AMD Chipset Drivers (Crimson Edition 16.7.3) 7/28/2016 - successfully installed
Secure boot enable AMD Chipset Drivers (Crimson Edition 16.7.3) 7/28/2016 - installation failed