lets say this:
if you run your fabric synced it is hard - as 4266MHz would equal 2133MHz on Fabric - not many Ryzen 3000 can handle this
best would be DDR4-3600CL16 - maybe even with lower manual timings like 3600CL14
this would mean your fabric runs with 1800MHz (as in stock) and this with low latency...
PC: R7 2700X @PBO + RX 580 4G (1500MHz/2000MHz CL16) + 32G DDR4-3200CL14 + 144hz 1ms FS P + 75hz 1ms FS
Laptop: R5 2500U @30W + RX 560X (1400MHz/1500MHz) + 16G DDR4-2400CL16 + 120Hz 3ms FS