I use my MacBook Pro 15" (late 2018) with a Razer Core X eGPU box and an "ASUS ROG Strix Radeon RX Vega 64 Overclocked Triple-Fan 8GB".
I have zero problems in Windows 10 with my PC via DisplayPort, but when I switch to using my Mac using HDMI (connected via HDMI-to-DisplayPort and HDMI-to-HDMI cables), every time I wake up my Mac from going to sleep mode, one of the 3 monitors doesn't come back up, just a black screen.
The monitor still appears as being detected (I look in System Preferences\Displays\Arrangement), and sometimes this is fixed if I turn the monitor off and back on again; but sometimes the monitor just flashes or goes from blank to working continuously, and the only fix is to restart my Mac and set it up to Never sleep.
Again, this does not happen with Windows 10, the 3 monitors are identical Dell 27" 2K.
alexkywalker