I just put a XFX R5 220 into my HP desktop. It has quad core processor and 8 GB of ram. I can only get two monitors to work at a time. The card came with 1 DVI, 1 HDMI,and 1 VGA. I when the HDMI is used, only that monitor and one of the others works. Any help is great, otherwise I'm returning this card for a EVGA that states 3 monitor support (as did this one).
According to this link from CNET concerning the Spec on your R5-220 it only supports a maximum of two monitors not three: XFX Radeon R5 220 Specs - CNET :
GENERAL
Interface TypePCI Express 2.1 x16
Max Resolution2560 x 1600
Max Monitors Supported2
Interfaces
DVI-D (dual link) HDMI VGA
From same website link:
VIDEO OUTPUT
Typegraphics card
Interface TypePCI Express 2.1 x16
Low Profilelow profile
Graphics Processor ManufacturerAMD
Graphics ProcessorAMD Radeon R5 220
Clock Speed650 MHz
Stream Processors Qty80
Max Monitors Supported2
Max External Resolution2560 x 1600
Max Resolution DetailsDVI: 2560 x 1600 / VGA: 2048 x 1536