Signal loss seems to be an common issue with AMD GPU's.
I have a RX7500XT that lose signal to the monitor while gaming (some games).
Removing and reinserting DP cable solves it sometimes, moving to another output sometimes.
I have tryed new cable, reinserting the GPU, flushing all traces of drivers without any luck.
AMD does not seem to be able to find a solution, nor the community for them.
Bought an nVidia GPU until case can be solved.