Hi there jb6699,
I had recently switched over to AMD GPUs as well. And yeah, the drivers seem a bit weird at first for sure. It would be really nice if they had "optimized" settings for each game that factored in your H/W & resolution / framerate...
First off, I have a 6900XT as well, and can assure you it will run pretty much anything at any resolution, EXCEPT if you enable Ray Tracing, (especially in Cyber Punk 2077). Unfortunately, Ray Tracing isn't great yet for AMD in most titles, although they are working on a competitor to DLSS, which will help a lot. To be completely honest, I may prefer non-RT anyways...
I had issues with the latest "BETA" driver, 21.3.2, so perhaps go back to the last Certified Release of 21.3.1 and try that. Look around for a Utility to completely remove AMD Drivers first, then install the non-BETA driver.
I have noticed some weird issues with some games that use say 5% GPU when running in a window on-screen, but then when you minimize them, the GPU usage jumps up by up to 25% (i would expect GPU usage to go down, if anything). I usually have at least one "idle" game running, but now I don't minimize them (although I usually close them when running something like Cyber Punk 2077). Open Task Manager or the Radeon driver before running the game, so you can see what the usage / memory etc. is when you see the issue. Just switch back to Task Manager (look at the GPU column on the Processes tab and the GPU info on the Performance tab) to see if you see something weird...
I Hope this Helps!
Ryzen 7 5800X • Radeon RX 6900 XT • 64GB RAM