Could possible be one more "disable hardware acceleration in web browsers and other software to fix strange issues" -thing.
Someone got rid of his issues by disabling MPO: https://community.amd.com/t5/drivers-software/amd-you-can-do-better-and-more-stable-drivers/m-p/5510...
"KabouterPlop1
Guys the solution is disable MPO
MPO is only active on mainscreen.
MPO only supports 8 bit color depth setting 10 bit color depth disengages it.
Disabling MPO fixes blackscreens and stuttering issues even flickering issues.
Windows Registry Editor Version 5.00
[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\Dwm]
"OverlayTestMode"=dword:00000005
The lack of this key means its enabled
MPO is a functionality of DWM desktop windows manager on windows 10 and windows 11"
run sfc /scannow in console (as admin) to check system files