Hi,
First lay out the foundations for your upgrade and read this handy guide.
How-to-install-a-GPU
Then, ask yourself, "Do I have a good enough Power Supply Unit?"
"Will my CPU be a good match for it?"
"Will I upgrade the CPU later?"
When You get the answer for it then the theoretical best course of action is use DDU to remove everything related to that card.
But I would just first uninstall drivers and install the new ones, only use DDU if it gives you any problems in the future.
Good Luck with the upgrade
The Englishman