you cant use radeon image sharpening yet, its bugged, actually the whole drivers are bugged so until it gets fixed its worthless. you should be able to use freesynce tho. mine worked with it and i havent heard of issues with that but the image sharpening is pretty well know/wide spread. not sure about the gpu scaling tho but prolly better to leave off just in case to be safe. or you could activate each one at a time and run some tests in between each activation to see exactly which one is causeing your system instabilities. id bet money tho that its the radeon image sharpening.
