Hello
I have 3 total monitors and the issue seems to be my Samsung, when i unplug it everything works fine but when it's plugged in none of the stated games run if i unplug the monitor launch the game then plug it back in it works.
EDIT: I did try a standard HDMI on the Samsung monitor still the same issue.
Asus XG27ACS - DISPLAYPORT - x2:
Samsung SMT27A950 - HDMI (DVI to HDMI):