As to VSR, the R9 290 series did not have support/capability for 4K vsr.
Going by old support list,
![290 vsr.PNG 290 vsr.PNG](/t5/image/serverpage/image-id/44204i05DAB1E48DD77328/image-size/large?v=v2&px=999)
And at a guess, you don't have vsr option due to the high res. of your monitor ?
As for the rest, i can't help, sorry.
My PC- Ryzen 5 5600x, B550 aorus pro ac, Hyper 212 black, 2 x 16gb F4-3600c16dgtzn kit, NM790 2TB, Nitro+RX6900XT, RM850, Win.10 Pro., LC27G55T.