How is your Monitor physically connected to the GPU card?
What is the Make & Model of your PSU, Motherboard, GPU, & CPU and Windows and AMD driver version installed.
Try physically removing and installing the GPU card back in the same PCIe Slot with power disconnected.
Are the GPU fans running?
Have you tried a different Video Output port on the GPU card?
Do your have video output from the GPU card in Windows Safe Mode?
Sounds like it overheated since it happened while playing a game.
If you install the GPU card in another computer and it has video Output than there is something wrong with your PC.
If you get no Video output in another computer you might want to open a AMD SUPPORT - Warranty ticket and see what they recommend for you to get video output on your GPU card from here: https://www.amd.com/en/support/contact-email-form