Sorry to hear that and I can understand how frustrating it must be.
- Can you be more specific about the symptoms
- List your hardware configuration (precisely - and which components you have changed already)
- What software you are running (OS, BIOS, drivers, installed programs that are running/active while problems occur - for instance everything next to clock, on bottom right corner in Windows)
- What steps have you have taken already to fix it
It is likely, that either something is broken or there is a hardware or software incompatibility
To reduce possible causes, I would recommend pulling out every device and gadget not necessary to boot and test the machine. If you have soundcard, DVD-player, capture card, USB drives, dongles and sticks, whatever, uninstall and unplug them. Use only one memory stick, remove non-necessary fans and gadgets, keep side panel open. Clear CMOS and flash BIOS to latest (assuming it supports your CPU), underclock CPU and GPU, keep XMP/(DOCP Asus) disabled. Only one SSD installed. Reinstall Windows 10. Install all updates to it. Download chipset and GPU drivers from AMD's website and install. If you see any yellow triangles in device manager, find drivers for them from motherboard makes site. Install one service (like Steam) and one game or 3DMark and test if problem persists. If it does, try another game that uses another DirectX version. If it still persists your hardware is simply broken and next step is to find out, which one.