I have this issue as well.
Playing on highest settings, with enhanced from AMD adranalin drivers (with profile). Switching the profile on/off does not change anything.
In Heart of Stone expansion during the scenes for a marriage quest I get an OpenGL error (see picture) 
stating to update the drivers. I am running the most recent drivers...
Computer Type: Desktop - custom build.
GPU: ASROCK AMD Radeon RX 5700 8GB GDDR6.
CPU: Ryzen 5 3600.
Motherboard: Gigabyte Aorus x570 Elite. Bios version f4j
RAM: 16GB (2x8GB) G.SKILL Trident RGB F4-3200C16D-16GTZR.
PSU: Gigabyte GP-G750H 750 WATT
Operating System & Version: Windows 10 Pro 1903.
GPU Drivers: Radeon software 19.8.2.