What changes are you making in Ryzen Master?
Check the Ryzen Master Settings to ensure PBO and CO options are being saved to BIOS.
Some settings in Ryzen Master are not saved to BIOS and must be re-applied after every boot. You can save them as a Profile within Ryzen Master. Then just restore the profile after every boot.
Ryzen R7 5700X | B550 Gaming X | 2x16GB G.Skill 3600 | Radeon RX 7900XT
Ryzen R7 5700G | B550 Gaming X | 2x8GB G.Skill 4000 | Radeon Vega 8 IGP
Ryzen R5 5600 | B550 Gaming Edge | 4x8GB G.Skill 3600 | Radeon RX 6800XT