I can't stand this problem anymore, it has been an issue for 3 whole years. It's driving me nuts! I know this new software strives to optimize better game performance but if this keeps going I'm gonna lose my freaking marbles!
I tried the many solutions told in older forums like disabling anti-lag or turning off the sync mode, I really just ended up disabling all the settings that is meant to enhance gamplay, since the software by default is already optimizing game performance, and the sound sizzles/crackling still persist!
AMD, please find a solution and really fix this in the next software update.