That's not the issue here, you're misunderstanding. I always load my tuning settings back after udating drivers, and I always propery uninstall the old drivers using DDU.
The problem here is that the tuning options for the GPU just DISAPPEARED from the tuning page, you have no ability to modify anything for the GPU. Look at the posted picture, under the GPU tuning that's all that's left. There's no options to modify anything anymore.