I have a dual monitor setup. But everyday at least a couple of times I get a notification that my cable isn't connected anymore at two screens at the same time. Nothing helps apart from rebooting. I still hear the sound of my pc (without lagging, or stuttering) but my keyboard is unresponsive. I am running the latest software.
PS: could you change the captcha needed to make an account on this website? I had to try ten times just to get in, this really can't be the goal of a captcha, right?
If using a single monitor prevents this error, you may contact AMD.
I have this issue too. Seems to happen when a game is on one monitor and a video running on the other. Further tests required to confirm as it doesn't happen always.
Identified a possible additonal culprit. It seems Watch2Gether plays really badly with the drivers and makes the games crash.