Sometimes I can't open AMD Radeon Software
I noticed that when I can't open it I have also problems with FreeSync. If I run game in fullscreen i have black screen. Turn off fullscreen or FreeSync in monitor (Acer Nitro VG220QBMIIX) and I have image. Reboot PC helps, but it is bothersome.
Radeon RX 580
Acer Nitro VG220QBMIIX
Windows 10 1909 Home
Yeah, i had it too sometimes with 19.12.3.
Problem still exists on 20.2.1