Hello,
I'm sorry to hear that you are having these issues, you would have much better luck finding people familiar with windows driver issues in https://community.amd.com/t5/pc-drivers-software/ct-p/PC_Drivers_and_Software
make sure to include you windows version, AMD driver version.
Unfortunately this error can be due to hardware issues, you have already updated and restarted.
It might be worth it to unplug your video card (unless its integrated) and look it over for any brown or burnt spots or unusual smells. Look at the pins and reinsert.
I would certainly post in the group I linked to above if that doesn't fix it, because this is just for "Prorender" a raytracing SDK.
First check out this post https://www.reddit.com/r/AMDHelp/comments/18a9fc2/error_code_43_device_manager/
If you look in the comments the poster was able to fix his error 43 and he lists the steps he did to fix his problem.
Good luck!