Hi, the appropriate pads for best results, is that if you are using a firmer thermal pads. It should be 2mm for Memory Chips and 1mm for VRM. Though if you plan on using a soft pliable pads, use 2.5mm for Memory Chips and 1.5mm for VRM. For the heat sink pads, 1mm should do and I would go for the GPU die until 4 years or so. But if you are replacing it too, think you should consider Thermal Grizzly Kryonaut should give outstanding result or even Noctua T-H1 or even ARCTIC MX-4.
You know my hot spot was hitting 110 and Junction was 82C. I was set all my fans all there full speed but only got 109C. I tried to figure out why? But then I realized that my power plan was at Saver Mode and knew the Prism was quietly spinning. So as soon as I put on Balanced, it started running at it potentials and so the hot spot went down to 100C. Just some information if you are running an air cooler.