I am having a similar issue with my 5700 XT. My PC got bricked with a driver update so I had to fresh install windows. With that I can use the integrated graphics to run windows, I try and re-install the drivers using Radeon software and after they install my PC can't display anything. I have to safe mode and DDU.
One solution said to install a window update, did that and I had to fresh install again.
There doesn't seem to be any acknowledgment from the devs that this is happening. If it isn't resolved soon I will be RMA'ing my card