Your Motherboard has one PCIe x 16 slot at PCIe 3.0. So any GPU card that can use that slot should work.
The RTX 3080 is a PCIe x 16 - 4.0 card.
But the RTX 3080 will also work on a PCIe x 16 - 3.0 Slot as per this article:
This GPU card is massive and takes up 2.5 slots on your motherboard in width. So make sure you have enough room on your computer case and a powerful PSU (Minimum of 750 Watts or higher) to be able to support this GPU card.