please post your computer Information including Make & Model of Motherboard, CPU, PSU and WIndows version installed.
Which new AMD GPU Card are you planning to buy?
You must be sure that your PSU is powerful enough to run the new GPU card. You can use this website as a reference to find out what is the minimum PSU wattage you need for various GPU cards installed on your computer: PSU REQUIREMENTS - RealHardTechX
As long as your Motherboard has PCIe 16x8 lane available and your Computer case is large enough , you can upgrade and install any latest GPU card.
NOTE: How powerful your CPU is also a factor since the CPU could bottleneck a powerful GPU card.
