After further testing i believe i did get a lot of flicerking due to LFC (Freesync Low Framerate Compensation)
Using CRU i did check i had very strange range of HZ from 56 to 75 hz on this Display, as i do not really care i want results did set it to 1 to 75 hz, and i was still getting some flickering. (On my main Display 240hz OMEN X 27) When playing Hogwarts Legacy
So the only thing i had open on second was Google Chrome with Stream on Kick,
Closed the Chrome and bang everything works........
Opened the stream on Edge works no flickering.
Still no idea why it would be causing that.
I am still thinking it could be caused by Cable maybe?
Didn't had this issue previously on RTX 2070 Super, and issue doesn't occur if am using Display as single