If they are in 'Local Disk (C:) > AMD', yes it's safe to delete them.
They are copies saved if needed to reinstall without having to download again.
Ryzen 5 5600x, B550 aorus pro ac, Hyper 212 black, 2 x 16gb F4-3600c16dgtzn kit, NM790 2TB, Nitro+RX6900XT, RM850, Win.10 Pro., LC27G55T..