I am using the AMD High Def Audio Device through Display Port and have speakers plugged into the headphone out plug on my monitor..
Give it try, I also had to turn the volume on the monitor OSD up to full..
AMD Ryzen 9 9900x, Asus Tuf Gaming RX 6700 XT, Asus Crosshair X870E Hero, 64gb Kingston DDR5 6000, Samsung 980pro 1tb NVME, Samsung 970 EVO Plus 1tb NVME, DeepCool Mystique 360 AIO, Antec Titanium 1000w.