Try the following:
Download the latest Intel HD 4600 driver from Intel's site.
Use DDU in Safe Mode to uninstall the Intel driver first without restarting, then uninstall the AMD driver with a restart.
Upon booting into Windows, install the AMD GPU driver first.
Restart.
See if the Settings window opens now.
If it doesn't, then there may be another issue at play. If the Radeon Settings window opens, install the Intel GPU driver.
Restart one more time.
This fix worked for me, i hope will help anothers with the same issue.
just leave feedback.
