New Adrenalin 22.7.1 Driver for Win 10 have a Bug. It is not possible to activate HDR mode on Win 10. If you are in the HDR window the System hangs and lags. I found no Fix. Only Driver Downgrade helps. I have HDR in Win 10 always on. With the new driver it is automatically disabled.
My System Specs are in the pictures below.
Monitor is: LG 27GL850 27' UltraGear 144 hz
If you go into the driver settings, under Graphics, scroll down near the bottom and turn off "10-Bit pixel format" then reboot, it fixes the issue.
(from the release notes of 22.7.1)
check you 10 Bit Pixel Setting as shown in the post from robertbrucks. (not 10 bit colors)