I'm playing Assassin's Creed Odyssey and the cave scenes are almost unplayable because the screen keeps getting washed out with very bright flashes of light. This happens with both the 20.4.1 drivers and the 20.2.2 drivers.. (maybe more so with 20.4.1? Not certain, just an impression).
This is a brand new build (AMD Ryzen 5 3600, on an Asus B450 board)., with a fresh install of Windows 10 64 bit. The card is an MSI Mech card.
Also, the graphics quality in Assassin's Creed Odyssey just looks pretty poor. Lots of tearing, and textures appearing and disappearing. Frankly the game looked better with my old Radeon RX590