Sometimes 3rd Party GPU controllers like Asus Tweak II or Sapphire Trixx or MSI Afterburner has conflicts with Radeon Settings or AMD Wattman specifically. Even if Wattman is not enabled.
I would suggest you install Tweak II and see if it has any conflicts with AMD Radeon settings or Wattman. If AMD driver starts have problems like GPU Fan control or some other issues, First thing I would do is uninstall Tweak II and see if that helps with your driver or GPU Fan issue issue.
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