ReactOS is an open-source OS that is based off an NT kernel, so it can run Windows based programs. However, lots of AMD (and many other) drivers don't work. Either the driver refuses to install, doesn't install correctly, or crashes and destroys the OS. While this could be because the OS is in alpha mode, I suspect that it could be because AMD never designed exe files with ReactOS in mind. I really hope AMD takes this seriously and will actually help out. Better driver support leads to more OS users. I hope AMD will make a 32 bit ReactOS driver for all new drivers.