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Please Post your computer Info as per AMD Forum rules: INFORMATION REQUIRED WHEN POSTING A QUESTION .
Then post any errors messages that you are getting when it crashes. Those error message can direct someone knowledgeable about your software or hardware to help.
Also what version of Adobe Lightroom do you have installed? Have you checked at Adobe for any recent updates since the new Windows version came out?
Does Adobe crash with a previous Driver installed?
Is it crashing on opening the app, or opening a picture or doing a particular function?