This became most apparent to me when using the latest version of Adobe Photoshop CC. I am running Windows 10 x64 (1709). This happens with 3 monitors. I have tested on two separate Intel based machines. One with a R9 290, and another with a RX480. I tested this with 17.11.1 and 17.11.4. Both versions had the same issue. 17.9.1 does not exhibit this issue.
The issue is very obvious when I am using Photoshop, and switch to another app (such as Chrome). When I switch back to Photoshop the cursor stutters and lags for a couple seconds before becoming responsive again (I am unable to interact with the application at this time, as I tried keyboard shortcuts and they did not respond). This happens EVERY time I switch back to Photoshop from another application. I have also noticed this problem at various times when using Windows. This was not an issue before 17.11. For now I am sticking to 17.9 because it does not cause problems.
The latest driver 17.12.1 still has this bug. More specifically. I move the mouse in a direction/pattern and the cursor will follow that path, even after I have finished moving the mouse. So the input is being sent from the mouse, but the input lag is multiple seconds. This happens EVERY time I switch into Photoshop.
ANOTHER WAY TO REPLICATE
When viewing settings in Windows 10. When I click the button for "Display" settings I have the same delay.
I am running multiple monitors.