When exiting a game the problem mostly occurs. I've read numerous threads but have not found a solution. I modified bios to keep memory clock @ 1250mhz and upped voltages to all 3 memory levels. After doing that I thought I was in the clear. The scrambled images and pixels no longer appear but my screen will flicker and have horizontal lines until the screen goes blank and the computer locks up. I have tried all the latest drivers to date and a clean install of Windows 10. Only thing I have not tried is testing the GPU in another PC.
8GB Mushkin Silverline DDR3 1600
R9 290x 4GB OC
FX-8120 OC 4.2GHZ
Windows 10 x64