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vodo, if you have a spare hdd try installing a fresh copy of w10 (i assume this is the one you are using now) and test with any driver from 17.9.x and below. I'm sure the problem will be fixed. I had run a few tests and after w10 updates (the major ones) you will face problems with drivers, maybe something 'breaks' and will give you a erratic behaviour, no matter what.
In my case the 17.10.x and newer i can't play gta 5 fullscreen or a crash related to DX3D occur. On the fresh W10 this problem was gone.
Maaaybe... just maybe, after running DDU try to run also the AMD Clean Uninstall Utility: