Firstly I'll apologise as I'm not that clued up when it comes to PC'.
My daughter was playing on her PC earlier and exited a game. On doing so the screen went blank rebooting didn't seem to work. After a period I took the HDMI cable out of the R9 380 and plugged it into the other HDMI (assume motherboard) and the issue was resolved. After searching some of the forum I've had a look at my device list which wasn't showing my R9 and is showing an Intel HD. By clicking on hidden I can now see the R9 however it's slightly greyed out and looking at the properties it states:
Currently, this hardware device is not connected to the computer. (Code 45)
To fix this problem, reconnect this hardware device to the computer
I've opened the PC to make sure there were no loose connections, which all seems fine. In addition the Driver Utility software has vanished and trying to re-install is met with a message stating it's not compatible.
Any help would be greatly appreciated.