FYI - Radeon Crimson 17.10.2 causes the process of creating an Eyefinity 2x2 display group to freeze, leaving all blank displays and the PC unresponsive, requiring a manual reboot. During the Eyefinity display group creation process, the PC freeze event occurs upon clicking Next after selecting "Use the current arrangement". Tried multiple times with same result. Uninstalled 17.10.2 and reinstalled 17.7.1, and all is back to normal.
Also, on another PC with the same specifications, the attempted 17.10.2 install resulted in a BSOD (system service exception - atikmdag.sys). Reinstalled 17.7.1 on that PC as well.
System: Desktop, Windows 10 Pro 64-bit, v1709, Build 16299.19 (Fall Creators Update)
Graphics: AMD HD7990, Radeon Crimson 17.7.1, without ReLive
Displays: (Four) Dell U2715H (As an Eyefinity 2x2 display group: 5120 x 2880 @ 60 hz), individually cabled DisplayPort 1.2 connections
Motherboard: ASRock X99 WS, BIOS P1.70
CPU: Intel Xeon E5-1650v3
PSU: SeaSonic Snow Silent 1050 (80+ Platinum)
Have you tried the Crimson Relive 17.10.3 ?