These are the requirements according to the data sheet for this product:
AMD Eyefinity technology supports up to six DisplayPort™ monitors on an enabled graphics card. Supported display quantity, type and resolution vary by model and board design; confirm specifications with manufacturer before purchase. To enable more than two displays, or multiple displays from a single output, additional hardware such as DisplayPort-ready monitors or DisplayPort 1.2 MST-enabled hubs may be required. Maximum two active adapters supported.