I have a problem with 17.2.1 too. Installation proceeds OK but after a reboot I get this
I've tried the update from within the Radeon software.
Then I downloaded from AMD.com and did a clean install. It doesn't seem to work.
I have a Asus R9 390x.
17.1.2 works fine so I'm rolling back to that. It's just 17.2.1 that has the problem.
I have a somewhat similar problem, when i updated my drivers my 2nd monitor either reflected (reflected as in doing the exact same thing) my 1st one treating it as one unit, or didn't detect it at all. What works for me is just uninstalling the new drivers, which works until i restart and then i have to repeat the process again.
I now get a different error when trying to download the new drivers, and at this point it won't let me download the new ones at all, even though i deleted them and it's the correct version. (error 175)
Sapphire R9 390
Intel i7 4790k
16GB 2133Mhz ram
Corsair RM750 750W PSU
Asus ROG Hero VII
I'm using sapphire nitro r9 390x, got same problem after installed Windows 10. but no problem with 17.2.1 (not WHQL). 17.2.1 WHQL is buggy.