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That would be controlled by the motherboard/BIOS, so the mobo vendor would be the best place to start.
Having said that, running 2 x RX480's in Crossfire mode with one running at 4X is probably providing really poor performance.
I read some manuals, and found out, that it is very comon, and can't be changed. I just have to find the right motherboard, and upgrade my system.
Thank you Ray for the correct answer